Report: 49ers QB Brock Purdy (toe) out 2-5 weeks

Sep 11, 2025, 8:39 AM Updated: Sep 12, 2025, 9:19 am

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San Francisco 49ers quarterback Brock Purdy will be sidelined for 2-5 weeks with a “turf toe variant,” NFL Network reported Thursday.

Head coach Kyle Shanahan on Wednesday called Purdy a “long shot” to play Sunday at New Orleans due to injuries to his toe and left shoulder.

Former first-round draft pick Mac Jones is expected to replace Purdy and will make his 50th career start in Week 2 against the Saints.

“Mac knows how to play the position, sees the field well,” Shanahan said. “Tough guy. He’ll hang in there and deliver the ball where it needs to go.”

Jones, who turned 27 last week, played 10 games with the Jacksonville Jaguars in 2024 after three seasons with the New England Patriots, who drafted him 15th overall in 2021.

Jones is 20-29 in his career as a starter, completing 65.9 percent of his passes for 10,590 yards with 54 touchdowns and 44 interceptions. He made the Pro Bowl after his rookie campaign in 2021.

Purdy, 25, completed 26 of 35 passes for 277 yards with two TDs and two picks in the season-opening 17-13 victory at Seattle. The 2023 Pro Bowl selection is 24-13 as the starter since being selected with the 262nd and final pick in the 2022 NFL Draft.

The third quarterback on the San Francisco depth chart is rookie Kurtis Rourke, a seventh-round pick out of Indiana.

–Field Level Media

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With star tight end George Kittle going on the Injured Reserve with a hamstring injury, the San Francisco 49ers have signed TE Messiah Swinson to their practice squad.

Luke Farrell and Jake Tonges are assumedly expected to fill in for a majority of Kittle’s minutes, but Swinson adds another option and depth at the position.

The San Francisco 49ers today announced they have signed TE Messiah Swinson to the team’s practice squad.

Swinson (6-7, 259) originally entered the NFL after signing with the Green Bay Packers as an undrafted free agent on April 30, 2024. In 2024, he spent time on the Packers and Carolina Panthers practice squads. After spending the 2025 training camp with Green Bay, he was waived by the Packers on August 26, 2025.

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