Injury to 49ers QB Brock Purdy (toe) could linger all season

San Francisco 49ers QB Brock Purdy will be dealing with his right big toe injury the rest of the season, 49ers coach Kyle Shanahan told the media.

BY FIELD LEVEL MEDIA

Nov 3, 2025, 2:28 PM

Follow on Google News

Watch: Rod Brooks: 49ers Rookie WR De'Zhaun Stribling is "the absolute real deal" | 1 min

San Francisco quarterback Brock Purdy will be dealing with his right big toe injury the rest of the season, 49ers coach Kyle Shanahan said after Sunday’s 34-24 road victory over the New York Giants.

The contest against New York marked the fifth in a row that Purdy missed. There was optimism he would be available against the Giants because he was listed as questionable and wasn’t ruled out for the game as in previous weeks.

But when the team turned in its pregame list of inactives, Purdy’s name was on it.

#49ers HC Kyle Shanahan revealed that QB Brock Purdy will be managing his turf toe all season. 🩹

The team will keep evaluating him week to week, and Shanahan confirmed they won’t rush him back.

Looks like it could be the Mac Jones show for a while. 👀 #FTTB pic.twitter.com/vuEZWrwVWJ

— 49ers & NFL News 24/7 (@49ersSportsTalk) November 2, 2025

“We’re trying to ease Brock out there in the practice stuff, but anytime you’re dealing with his turf toe, it’s something that probably won’t fully go away all year regardless of when he comes back,” Shanahan said. “He’s going to always have to deal with a little bit. … So it’s really about just assessing when’s the best time to come back that you have to deal with it the least. It’s a little bit of a tricky decision.”

Shanahan said Brock Purdy “wasn’t that close” to being active Sunday despite being listed as questionable. Adrian Martinez served as the No. 2 quarterback behind Mac Jones.

“I just want to make sure he gets 100% better and won’t put him out there too early,” Shanahan said. “Thought about it as a possible backup or emergency, but I think the more time we get, the better.”

Brock Purdy was initially hurt during the season-opening 17-13 victory over against the Seattle Seahawks and missed the next two games. He aggravated the injury during a 26-21 home loss against the Jacksonville Jaguars in Week 4.

Jones has started seven games and San Francisco (6-3) has won five of them. He passed for 235 yards and two touchdowns against New York.

Also, the 49ers fear that rookie defensive end Mykel Williams tore the ACL in his right knee in the fourth quarter while pressuring Giants quarterback Jaxson Dart. Williams, the 11th overall pick in the 2025 draft, will undergo further testing on Monday.

“He’s just down and you never know. Hopefully it’s not the worst but, if it is, hey, that sucks for this year,” Shanahan said. “But that’s all it sucks for. You’ll be back next year and this won’t affect you at all.”

–Field Level Media

More on Brock Purdy & the 49ers from Sactown Sports

The San Francisco 49ers are now 6-3 on the season following Sunday’s win over the New York Giants, and now all eyes shift to the injury report for Brock Purdy’s Week 10 designation.

During Monday morning’s edition of The Carmichael Dave Show with Jason Ross, The Athletic’s Matt Barrows joined the show to share his thoughts on the 49ers’ win over the Giants, share an injury update on QB Brock Purdy (toe), and much more.

Plus, are the 49ers in a good spot with Mac Jones under center if Brock Purdy needs more time to heal?

Be sure to listen to and watch the entire interview with Matt Barrows right here or on the Sactown Sports 1140 YouTube page.