49ers QB Brock Purdy (toe) has ‘a chance’ to play in home opener

Per San Francisco 49ers head coach Kyle Shanahan, starting QB Brock Purdy “has a chance” to play Sunday vs. Arizona.

Sep 18, 2025, 11:41 AM

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Backup quarterback Mac Jones got the job done in New Orleans, filling in for Brock Purdy who is dealing with a toe injury.

Originally listed as out for 2-5 weeks after suffering the injury in Seattle during game one, it seems like the starting QB may be ahead of schedule.

San Francisco’s head coach, Kyle Shanahan, told reporters on Wednesday that Purdy “will be limited” in this week’s practice.

Purdy is practicing today!!!

💯👀💯 pic.twitter.com/QLmhqbdBlc

— 95.7 The Game (@957thegame) September 17, 2025

When questioned about his availability for their week three home opener against Arizona, Shanahan said Purdy “does have a chance” to play.

For him, it’s all about getting a gauge for how the Iowa State product is feeling headed into Sunday.

what he thinks he can do today, what he thinks he could do tomorrow, Friday and Sunday,” Shanahan said.

”Really doesn’t have anything to do with how Mac played, whether it was good or bad. Doesn’t really affect that. I just talk about where Brock’s at right now.”

The 49ers and Cardinals both own 2-0 record, competing within the NFC West.

We’ll see if Purdy is good to by then, or if it’ll be another opportunity for Jones to fill in.

More San Francisco 49ers coverage on Sactown Sports

Mac Jones threw three touchdown passes as Brock Purdy’s replacement and the visiting San Francisco 49ers held off the New Orleans Saints 26-21 on Sunday afternoon.

Jones made his debut for the 49ers (2-0) in place of Purdy, who is sidelined by a toe injury, and completed 26 of 39 for 279 yards.

Spencer Rattler matched Jones’ three touchdown passes while completing 25 of 34 for 206 yards and Alvin Kamara rushed for 100 yards on 21 carries for the Saints (0-2).

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